Understanding calorie intake, energy expenditure, metabolic adaptation, insulin, hormones, and the physiology of a weight-loss plateau

Abstract

GLP-1 receptor agonists can produce substantial weight loss by altering appetite, satiety, food reward, glucose regulation, and other physiological proces...

Use the Advantage to Build a System That Lasts

GLP-1 medications have changed weight loss for millions of people.

For many, one of the biggest changes is simple: losing weight becomes easier.

Hunger may decrease. Cravings and food noise may become quieter. Smaller portions may feel more satisfyin...

What the New British Medical Journal Review Really Shows

GLP-1 receptor agonists such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) have changed obesity treatment. Many people are losing significant weight, often for the first time in years.

But a new systematic review publ...